Recent research by the University of South Australia indicates that maternal obesity during pregnancy significantly affects the postnatal health of the fetus. According to the study, conducted by researchers in Australia, excessive weight gain during pregnancy increases the risk of metabolic complications in the fetus (male) after birth, including liver disease and diabetes.
Maternal obesity increases the concentration of androgens in the uterus, according to the research team. It has been revealed that androgens alter the signals sent by the fetus (male) liver. As a result of these altered signals, the body prioritizes growth over health.
Androgen refers to all substances that represent the action of male hormones. It is a hormone that primarily secreted in the testes of males and some are also secreted in the adrenal cortex and ovaries of females. The most famous one is testosterone.
Dr. Ashley Meakin, who participated in the research, pointed out that while androgens play a crucial role in endowing male characteristics to the fetus, excessive levels can not only lead to overgrowth of the child but also have negative effects on liver function after birth. However, in the case of female fetuses, the pathways transmitting such signals are blocked, thus mitigating these risks.
Dr. Ashley Meakin, who participated in the research, explained that if the mother was obese during pregnancy and if the birth weight of a male child exceeds 4kg, the likelihood of developing non-alcoholic fatty liver disease and diabetes in adulthood is higher.
Professor Jane Morrison, the research director of the Adult Health Research Group, emphasized the importance of a balanced diet for pregnant women above all else. She stressed that excessive dieting to prevent obesity can also put the fetus at risk of malnutrition.
Professor Morrison emphasized that both being born too small or too large can have negative effects on the future health of the fetus. She stressed the importance of being born at the right size and time.
This study was published in "Life Sciences" magazine.
source: kormedi.com